EIC Transition 2024: 40 projects picked to move lab breakthroughs toward market readiness

Brussels, January 22nd 2025
Summary
  • The European Innovation Council selected 40 projects in the 2024 EIC Transition call to mature technologies toward market readiness.
  • Each successful proposal is eligible for a grant of up to €2.5 million subject to signing a grant agreement.
  • Nineteen selected projects originate from ERC Proof of Concept work and this edition allowed new source categories under Horizon Europe pillar 2 and certain Horizon 2020 streams.
  • The call attracted a large pool of submissions with 390 eligible proposals and participants from 21 EU and associated countries.
  • Selected projects gain access to EIC Business Acceleration Services and a fast-track route to EIC Accelerator for commercialisation support.
  • Examples in the portfolio include HeartWise for right ventricular mechanical support, FOREVER-WATER for PFAS destruction, and UPSPRING for ultralow power spintronic devices.

EIC Transition pushes 40 deep tech projects from lab to market

On 22 January 2025 the European Innovation Council and the European Innovation Council and SMEs Executive Agency announced 40 projects selected under the 2024 EIC Transition call. The call was the most popular to date in terms of submissions for this scheme. The agency says the 40 proposals were picked from 390 eligible submissions and that each successful proposal will receive a grant of up to €2.5 million once the grant agreement is signed. The projects come from 21 EU Member States and Horizon Europe associated countries and span a broad range of scientific and technological fields because this funding line does not impose predefined thematic restrictions.

What EIC Transition is intended to fund

EIC Transition purpose and scope:EIC Transition targets technologies that have already produced substantive research results. The funding is intended to mature those outputs, validate them in application relevant environments and begin to build a business case to reach market readiness. Eligible project origins include EIC Pathfinder and its predecessor FET, ERC Proof of Concept projects, Research and Innovation Actions funded under selected Horizon 2020 streams and Horizon Europe pillar 2, and in some cases research funded under the European Defence Fund when the applications focus on civil use.
Technology readiness and the EIC Transition:The scheme is oriented to projects that must increase their Technology Readiness Level or TRL toward application. TRL is a standard metric that ranges from 1 for basic research to 9 for proven, operational systems. EIC Transition typically supports projects that move from mid TRLs toward demonstration in realistic environments and initial market validation. The grant aims to cover the technical validation and the initial business planning required for commercial uptake.

Portfolio highlights and illustrative projects

The press material lists a wide array of technologies from medical devices to environmental remediation and semiconductor components. Three representative projects noted by the EIC illustrate the diversity and ambition of the portfolio but also underline the scale of the challenge to translate lab prototypes into reliable, regulated, and commercially viable products.

HeartWise

HeartWise aims to develop a fully implantable mechanical circulatory support device dedicated to right ventricular support. The project brings together two Proof of Concept technologies: circulation support devices that operate without external power and patient-specific cardiovascular surgical planning. The stated goal is a fully implantable mechanical circulatory support prototype that eliminates external power packs and control units. This is ambitious given the high regulatory bar, the need for long-term in vivo validation and the safety requirements for implantable cardiac devices.

FOREVER-WATER

FOREVER-WATER addresses per- and polyfluoroalkyl substances or PFAS, a persistent class of contaminants sometimes called forever chemicals. The project proposes a chemical-free treatment system based on graphene-enabled electrochemical technology that aims to destroy PFAS across applications from groundwater to industrial effluents. PFAS destruction is a high-impact goal but claims of efficient, scalable destruction under real world conditions require careful, independent validation, particularly because PFAS chemistries are diverse and treatment efficacy depends on matrices and concentrations.

UPSPRING

UPSPRING proposes a new FerroElectric Spin-Orbit device that the team says could reduce chip energy consumption by up to 1,000 times compared with current microelectronics. The project frames this work as supporting EU ambitions to increase its share of the global semiconductor market and to strengthen digital sovereignty. Radical gains in energy efficiency are attractive but will require replication across fabrication flows and integration into existing manufacturing ecosystems for any meaningful market impact.

Numbers, provenance and eligibility

According to the announcement, the 40 selected projects were chosen from 390 eligible submissions. A large share of the successful proposals originate from European Research Council Proof of Concept projects with 19 explicitly flagged. This edition also permitted actions stemming from Horizon Europe pillar 2 and selected Horizon 2020 streams including Societal Challenges and Leadership in Industrial Technologies to apply. The pool of applicants reportedly included private companies, universities and research organisations across multiple countries.

MetricValue
Selected projects40
Eligible submissions for this call390
Projects originating from ERC Proof of Concept19
Participant countries represented21 EU Member States and associated countries
Maximum grant per successful proposalUp to €2.5 million, funding subject to grant agreement signature
Thematic restrictionNo predefined thematic priorities
Next EIC Transition cut-off date17 September 2025

Full list of selected proposals and recommended budgets

The agency published the portfolio of the 40 selected projects. The table below reproduces the submission metadata published by the EIC. Note that the official notice reiterates that payment of the advertised grant amounts depends on signature of the grant agreement and that some budget figures published as 'recommended' in selection documents may include items such as indicative costs or investment components pending final negotiation.

AcronymProposal TitleDuration (months)CountryCoordinating organisationRecommended Budget
FLAIRVISIONFirst-in-human flexible array implant to restore vision36BEKATHOLIEKE UNIVERSITEIT LEUVEN2,495,144.15 €
ARISEARISE - Advanced RNA Inhalation Solutions anchored in Evolved dry powder technology.36DERNhale GmbH2,490,248.75 €
HQS-NextNMRNext-Gen NMR Prediction and Analysis: A Cutting-Edge Tool for High-Precision Structure Identification24DEHQS QUANTUM SIMULATIONS GMBH2,499,990.63 €
IMMUNOCONControlling immunity with small molecules for a better therapy24DEEMUNO Therapeutics GmbH2,484,700.99 €
NEUROGATEChronic Deep-Brain Micro-Endoscopy in Behaving Animal Models: Advancing Holographic Endoscopes Along the Path to Global Availability.36DELEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V.2,498,226.98 €
CIRCULAR VISION 2.0Circular DNA in screening and prognosis of pancreatic cancer30DKKOBENHAVNS UNIVERSITET2,499,824.00 €
COANANext Generation Software Supply Chain Security24DKCoana ApS2,496,249.98 €
DECODEDirect Coherent Detection Optical Transceiver30DKPhanofi Aps2,500,000.00 €
StealthStentPolymer-based Stealth Coating of Hemocompatible and Absorbable Stents36DKBIOMODICS APS2,495,679.00 €
EndoCartoScopeEndocartoScope: Transforming any Endoscope into a Smart Device for Intraoperative 3D Localization, Navigation and Mapping36ESUNIVERSIDAD DE ZARAGOZA2,498,425.00 €
FOREVER-WATERDestruction of forever chemicals in water using chemical-free water treatment system36ESFUNDACIO INSTITUT CATALA DE RECERCA DE L'AIGUA2,487,471.17 €
MATCATH2.0Matteco PGM-free Cathodes for Next Generation Hydrogen Production36ESMATTECO TEAM SL2,498,996.88 €
MEDiCSAnticancer approach based on the Metabolic Disruption of Cancer Stem Cells with high effectivity across a wide range of solid tumours36ESUNIVERSIDAD DE SANTIAGO DE COMPOSTELA2,498,015.63 €
SkinEngineeringRevolutionizing Skin Health with our Advanced Engineered Biotherapeutics36ESUNIVERSIDAD POMPEU FABRA2,500,000.00 €
VIVA-ELISAVIVA-ELISA: Advanced Laboratory Test for Rapid Detection of NLRP3 Inflammasome Activation in Critical Septic Patients36ESVIVA IN VITRO DIAGNOSTICS, S.L.2,500,103.89 €
COOLEDLight emitting cryo-cooler48FIAALTO KORKEAKOULUSAATIO SR2,729,244.58 €
AOscopyAdaptive Optics-enhanced multiphoton microscopy36FRIMAGINE OPTIC2,473,325.00 €
GlycoBoostPrecision control of glycosylation to open a new era of therapeutic antibodies30FRKYRON.BIO2,499,540.38 €
METAPRINTNano-imprint lithography of titania-based metaoptics36FRSOLNIL2,473,250.00 €
RS-NeuroMarkersAdvancing stroke care with cutting-edge ultrasound biomarkers for Neurocritical Care24FRResolve Stroke2,495,000.00 €
SQELETONScalable Qubit Readout to Resolve Superconducting Quantum Computing’s Skeleton in the Closet30FRSILENT WAVES2,499,406.25 €
ScanNanoTreatRadically New Cancer Therapy Based on Advances in Nanotechnology and Photonics for Simultaneous Imaging and Treatment of Solid Tumours36FRUNIVERSITE LYON 1 CLAUDE BERNARD2,499,911.25 €
UPSPRINGUltralow power ferroelectric spintronic components for logic and artificial intelligence36FRNELLOW2,500,000.00 €
SMARTHEALSmart Implant for Magnetic Anastomotic Healing and Leakage Evaluation30IECOLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN2,499,815.52 €
NeutroFlowDevelopment and validation of a pan-cancer neutrophil biomarker test for predicting clinical benefit from immunotherapy based on flow cytometry analysis of blood samples36ILOncoHost2,500,000.00 €
TIMNanoRESTORING IMMUNITY CONTROL OF GI CANCERS36ILTEL AVIV UNIVERSITY2,192,750.50 €
3DPATHEnabling the transition to 3D digital pathology36ITClepio Biotech S.r.l.2,499,933.00 €
Q-SPINQUANTUM SYSTEM FOR POLARIZATION-BASED INTERNET NETWORKING36ITTHINKQUANTUM SRL2,499,683.30 €
InQubateIntegrated Quantum Network Node using Chip-based Qubit Devices24NLDelft Networks B.V.2,500,000.00 €
PAQAALDeveloping Photonic-Electronic Analog Application-Specific Integrated Circuits for a Quantum Secure Coherent Link36NLCublQ B.V.2,499,375.00 €
POPCORNAdvancing Semiconductor Reliability with Device Aware Testing for Next-Generation Non-Volatile Memory Technologies30NLTECHNISCHE UNIVERSITEIT DELFT2,499,375.00 €
SIGHTEDreStoring sIGHt wiTh a neuroprosthEsis for the blinD30NLPHOSPHOENIX BV2,499,750.00 €
VIVIDClinical Validation of In Vivo Imaging for Detecting Immune Dynamics36NLWAGENINGEN UNIVERSITY2,443,726.00 €
SpermotileCultivating hope one star sperm at a time30NOUNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET2,499,906.25 €
ZeroCarbIntermediate temperature catalytic methane splitting for a swift energy decarbonisation30PTHYCARB Lda2,476,872.59 €
Repro-TILBreakthrough Neoantigen-specific Tumor-Infiltrating Lymphocyte Therapies Through Novel Dendritic Cell Reprogramming36SEASGARD THERAPEUTICS AB2,492,867.64 €
HeartWiseArtificial Right-Heart without External Power from Bench-to-Bedside36TRKOC UNIVERSITY2,498,243.75 €
CResPulsePacing with Digital Twins of Brainstem Neuronal Circuits as an Effective Therapy for Chronic Cardiac Disease36UKUNIVERSITY OF BATH2,491,156.00 €
PERFORMPerovskite Photon Counting X-ray Detectors for Medical Imaging.36UKClarity Sensors Limited2,494,268.00 €
WILLOWISPWireless, Low-Cost, Low-Power Integrated Sensor Photonics36UKResolute Photonics UK Ltd2,498,961.45 €

Support attached to the grants and conditions

EIC Business Acceleration Services:Selected projects will have access to EIC Business Acceleration Services, which include coaching, mentoring and partnering events. The services are intended to help teams build commercial strategies, engage with investors and prepare for scaling. These services can be useful, but coaching alone rarely closes the financing gap between prototype validation and industrial scale up.
Fast-track to EIC Accelerator and investment:Projects funded by EIC Transition are eligible for a fast-track procedure to access the EIC Accelerator, which supports commercialisation and scale up with grants and equity investments via the EIC Fund. Accessing later-stage scale funding often depends on demonstration of market traction and private co-investment. The announcement stresses that grant payments depend on the signature of a grant agreement and that further negotiation can change the final funding arrangement.

Critical perspective and practical challenges

The EIC Transition instrument is important because it explicitly targets the valley of death between academic proof of concept and commercial deployment. The selection of 40 projects among hundreds of applicants shows strong demand. The announcement does not, however, remove the well known obstacles that deep tech innovators face. These include regulatory approvals especially in health and medical devices, scale up and manufacturing integration for hardware and semiconductors, long and costly real world testing for environmental remediation, and the need to attract significant private follow-on capital. Observers should watch the conversion rate from selection to signed grant agreements and then from awarded grants to measurable commercial traction.

One operational point to note is that some published 'recommended budget' figures in selection documents appear higher than the stated cap of €2.5 million. That can reflect reporting formats, multi-component funding including investment streams, or provisional figures ahead of final grant negotiations. The legal notice attached to Commission pages reminds readers that published material is indicative until formal agreements are signed.

Next steps for applicants and observers

Applicants invited to grant preparation will move into negotiation phases. Projects invited for grant preparations are expected to start in April or May 2025 according to earlier timelines published by the EIC. The next EIC Transition deadline is 17 September 2025. Interested teams should also consider national or regional funding channels, investor outreach and standards compliance early in their development plans.

Where to follow the process:Further details, official documents and the list of beneficiaries are published on the EIC and EISMEA web pages. The EIC publishes work programmes, guidance and contact points for business coaches and evaluators. For those tracking outcomes, conversion of awards into signed grants and subsequent commercial milestones are the key indicators to monitor.

Background on the implementers

The EIC Transition call and the wider EIC portfolio are implemented by the European Innovation Council and SMEs Executive Agency or EISMEA on behalf of the European Commission. The EIC Fund provides equity-style instruments and the EIC Accelerator performs later stage support. EISMEA manages calls, evaluation and grant preparation, while the EIC Fund and partners coordinate co-investment. Public documents from these bodies set the legal and practical framework for selection, contracting and data protection.