EIB lends €10 million to EIC-backed Polish medtech SDS Optic to scale photonic cancer detection platform

Brussels, October 2nd 2023
Summary
  • The European Investment Bank agreed a loan of up to €10 million to Polish company SDS Optic to scale the inPROBE photonic biosensing platform.
  • The loan is backed by the InvestEU programme and follows nearly €4 million in EIC Accelerator support for SDS Optic's SDS OmiProbe project.
  • inPROBE is presented as a single cell resolution, in vivo photonic immunoassay targeting faster cancer diagnosis and treatment monitoring.
  • The financing targets research and development and commercialisation, with a particular focus on accelerating market readiness and manufacturing scale up.
  • Key caveats remain including clinical validation, regulatory approval, reimbursement strategies and adoption by health systems.

EIB supports scaling of SDS Optic's photonic cancer detection platform

The European Investment Bank signed a loan agreement for up to €10 million with SDS Optic Inc., a Lublin based Polish medtech company listed on the Warsaw Stock Exchange under the ticker NC:SDS. The funding is intended to accelerate research and development and the commercial roll out of inPROBE, a photonic biosensing platform the company bills as capable of real time, single cell resolution diagnostics and monitoring of cancer. The operation is backed by the InvestEU programme, which the European Commission designed to mobilise large-scale public and private investment across strategic sectors.

Deal specifics and public backing

The EIB statement and associated press material make three practical points. First, the loan facility is up to €10 million and is intended to support development and commercialisation activities. Second, SDS Optic previously received almost €4 million through the European Innovation Council Accelerator under the SDS OmiProbe project. Third, the operation benefits from InvestEU backing which increases the EIB's risk capacity and is meant to leverage further private capital.

EIB loan:Up to €10 million provided by the European Investment Bank to SDS Optic for R and D and scale up of the inPROBE platform. The public material describes the loan as supporting dynamic growth and faster market entry.
InvestEU support:The agreement was made possible with InvestEU backing. InvestEU provides an EU budget guarantee to implementing partners and aims to mobilise at least €372 billion in additional investment for the 2021 to 2027 period. The programme includes a guarantee of about €26.2 billion to increase risk bearing capacity of financial partners.

Public comment in the coverage highlighted institutional support for innovation and health technology. EIB Vice President Teresa Czerwińska said the bank prioritises research and innovation and welcomed cooperation with an ambitious Polish medtech company. European Commissioner for the Economy Paolo Gentiloni said the investment underlines the EU commitment to improving diagnostics and to positioning Europe at the cutting edge of health technology. SDS Optic's CEO Marcin Staniszewski framed the loan as an acceleration of commercialisation and a vote of confidence after EIB verification of the company's scientific data.

What inPROBE is and how it works

inPROBE platform:SDS Optic's inPROBE is presented as an in vivo photonic immunoassay platform. The core element is an optical fibre tip around six microns in diameter that is functionalised with antibodies. The device is intended to detect molecular markers at single cell resolution directly in tissue. SDS Optic positions the technology as useful for faster cancer diagnosis, treatment monitoring and real time drug delivery assessment.
Single cell HER2 detection:The company highlights a specific application for HER2 positive breast cancer diagnostics. HER2 is a well known protein biomarker used to stratify breast cancer patients because it can determine eligibility for targeted therapies. SDS Optic claims it has developed the first single cell resolution immunoassay for real time HER2 diagnosis using photonic techniques.
Photonic biosensing explained:Photonic biosensing uses light to probe biological interactions. Methods can include optical fibres, surface plasmon resonance, fluorescence excitation and scattering. Advantages often cited are high sensitivity and the potential for label free or minimally invasive measurements. The practical performance of any photonic sensor depends on signal to noise ratio, specificity of the biological recognition element, sample handling and the clinical workflow in which it is used.

Funding history and timeline

SDS Optic has combined EU innovation grant funding with private and institutional financing to progress its technology. The EIC Accelerator previously provided nearly €4 million under a project called SDS OmiProbe. The EIB loan is positioned as follow on capital to move the product beyond prototype and early validation toward commercial scale and market introduction.

StageInstrumentAmount / scopePurpose
Early development and demonstrationEIC Accelerator (SDS OmiProbe)Nearly €4 millionPrototype development, technical and business validation
Scale up and commercialisationEIB loan with InvestEU backingUp to €10 millionFurther R and D, manufacturing scale up, market entry
Policy backingInvestEU guaranteeEU budget guarantee of €26.2 billion for partners, target mobilisation €372 billionIncrease implementing partner risk capacity and attract private co investment

Why the EU institutions are promoting this deal

European institutions consistently present such operations as advancing three policy goals at once. First, health outcomes by improving diagnostics and treatment monitoring. Second, industrial competitiveness by developing high value deep tech medtech in Europe. Third, territorial cohesion by supporting growth in less developed regions. The EIB specifically noted the project will support advanced research activities in a less developed region of the EU by per capita income measures.

The EIB also frames the loan in the context of its broader support for research, innovation and human capital. The bank reported backing of nearly €18 billion globally for these sectors in 2022 and €4.65 billion in Poland between 2018 and 2022.

Open questions and practical challenges

Public announcements typically emphasise potential. A balanced view requires highlighting the technical, clinical and commercial steps that remain. These include independent clinical validation, regulatory clearance in relevant markets, integration into clinical workflows, convincing clinicians and hospital procurement bodies, securing reimbursement, and scaling reliable manufacturing for medical devices.

Clinical validation:Claims of reducing diagnostic time from months to minutes are ambitious. They require prospective clinical studies that compare the device against established diagnostic standards. Peer reviewed data, multi centre trials and reproducibility across operators are needed before clinicians and payers will change practice.
Regulatory approval and reimbursement:Medical devices face regulatory pathways that vary by jurisdiction. In the EU the conformity assessment and CE marking process for in vitro diagnostic and active implantable devices requires clinical evidence proportional to risk. Obtaining reimbursement from public health systems requires evidence of clinical utility and cost effectiveness. Both processes can be time consuming and resource intensive.
Manufacturing and quality systems:Moving from lab prototypes to regulated production needs investments in quality management, supplier controls and production scale up. For a fibre tipped probe at micron scale, consistent surface chemistry and sterility are practical manufacturing challenges.
Market adoption:Hospitals tend to be conservative and risk averse about new diagnostic hardware. Adoption depends on clear pathways for use, training for clinicians, compatibility with existing instrumentation and convincing value propositions set against incumbent tests and procedures.

Context in the EU innovation landscape

The SDS Optic operation is a typical example of how the European innovation ecosystem blends grant support and concessional finance to de risk early stage deep tech. The EIC Accelerator provides non dilutive funding and grants to help reach key validation milestones. Instruments like InvestEU and EIB loans aim to bridge later funding gaps that neither early stage grants nor private venture capital always cover. This mix is designed to improve the odds that technologies developed in Europe reach commercial scale within the single market and beyond.

However the availability of public finance does not eliminate market risk. For many deep tech medtech firms the hardest steps are clinical proof of concept, regulatory clearance, achieving reimbursement and convincing clinicians to change practice. Each step requires different capabilities and partners, including hospital networks, contract research organisations, regulatory consultants and early adopter clinicians.

Implications for regional development and cohesion

EIB communications highlighted that the transaction supports advanced research activity in a less developed region of the Union. That aligns with EU cohesion goals which pursue balanced territorial development. Deploying high technology manufacturing and R and D in places outside major innovation clusters can create jobs and skills locally. The challenge will be sustaining long term growth and building supply chains for medtech components.

Conclusion

Institutional backing from the EIB and InvestEU is meaningful for a small medtech company. It should improve SDS Optic's ability to fund R and D and to enter markets faster than without such support. That said, the announcement is an early stage financing milestone rather than proof of clinical or commercial success. Independent clinical validation, regulatory approvals and concrete adoption by health systems remain necessary before the technology can deliver the broad patient benefits claimed by the company and promoted by institutional partners.